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NKX2-8 Protein (Myc-DYKDDDDK Tag)

NKX2-8 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2727355
发货至: 中国
  • 抗原 See all NKX2-8 蛋白
    NKX2-8 (NK2 Homeobox 8 (NKX2-8))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 2
    • 2
    HEK-293 Cells
    标记
    This NKX2-8 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human NKX2-8 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NKX2-8 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    NKX2-8 (NK2 Homeobox 8 (NKX2-8))
    别名
    Nkx2-8 (NKX2-8 产品)
    别名
    NKX2.8 Protein, NKX2H Protein, Nkx2-9 Protein, Nkx-2.9 Protein, Nkx2-8 Protein, Nkx2.9 Protein, tinman Protein, NK2 homeobox 8 Protein, NK2 homeobox 9 Protein, NKX2-8 Protein, Nkx2-9 Protein, Nkx2-8 Protein
    背景
    The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.
    分子量
    25.7 kDa
    NCBI登录号
    NP_055175
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