ISCU Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all ISCU 蛋白
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ISCU protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human ISCU / NIFUN (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ISCU 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- 别名
- Nifun (ISCU 产品)
- 别名
- nifun Protein, zC191D15.3 Protein, si:ch211-191d15.3 Protein, 2310020H20Rik Protein, HML Protein, ISU2 Protein, NIFU Protein, NIFUN Protein, hnifU Protein, RGD1309562 Protein, AA407971 Protein, Nifu Protein, Nifun Protein, iron-sulfur cluster assembly enzyme ISCU, mitochondrial Protein, iron-sulfur cluster assembly enzyme Protein, iron-sulfur cluster assembly enzyme a Protein, LOC409130 Protein, ISCU Protein, iscua Protein, Iscu Protein
- 背景
- This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
- 分子量
- 15.1 kDa
- NCBI登录号
- NP_055116
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