Neuroserpin Protein (Transcript Variant 1)
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- 抗原 See all Neuroserpin (SERPINI1) 蛋白
- Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- 特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
- 产品特性
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- Recombinant human Neuroserpin / SERPINI1 (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- 内毒素水平
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by the dose-dependent stimulation of the proliferation of rat C6 cells using a concentration range of 0.3-0.6ug/mL.
- Top Product
- Discover our top product SERPINI1 蛋白
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serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) (AA 17-410) protein (GST tag)
SERPINI1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) protein (His tag)SERPINI1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) (AA 17-410) protein (His tag)Crystallography grade SERPINI1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - 限制
- 仅限研究用
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- 缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- 注意事项
- Resuspend the protein in the desired concentration in proper buffer
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
- 别名
- Neuroserpin,serpini1 (SERPINI1 产品)
- 别名
- PI12 Protein, neuroserpin Protein, AI837402 Protein, Ns Protein, PI-12 Protein, Spi17 Protein, CG9453 Protein, Dmel\\CG9453 Protein, Serp2 Protein, Sp4 Protein, Spn4 Protein, Spn4A Protein, dSerp2 Protein, sp4 Protein, spn4 Protein, raPIT5a Protein, SERPINI1 Protein, pi12 Protein, serpini1l Protein, si:ch211-167c22.4 Protein, serpin family I member 1 Protein, serine (or cysteine) peptidase inhibitor, clade I, member 1 Protein, Serpin 42Da Protein, serpin peptidase inhibitor, clade I (neuroserpin), member 1 Protein, serpin family I member 1 L homeolog Protein, SERPINI1 Protein, Serpini1 Protein, Spn42Da Protein, serpini1 Protein, serpini1.L Protein
- 背景
- This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- 分子量
- 44.8 kDa
- NCBI登录号
- NP_005016
- 途径
- Regulation of Hormone Metabolic Process
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