WHSC2 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all WHSC2 蛋白
- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This WHSC2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human NELF-A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product WHSC2 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
- 别名
- Nelf-A (WHSC2 产品)
- 别名
- BcDNA:SD07139 Protein, CG5874 Protein, Dmel\\CG5874 Protein, NELF Protein, NELF-A Protein, Whsc2 Protein, fi75f03 Protein, whsc2 Protein, wu:fi75f03 Protein, MGC85474 Protein, WHSC2 Protein, nelfa Protein, nelf-a Protein, p/okcl.15 Protein, Whsc2h Protein, Negative elongation factor A Protein, negative elongation factor complex member A Protein, negative elongation factor complex member A L homeolog Protein, negative elongation factor complex member A, Whsc2 Protein, Nelf-A Protein, Nelfa Protein, nelfa Protein, nelfa.L Protein, NELFA Protein
- 背景
- This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
- 分子量
- 57.1 kDa
- NCBI登录号
- NP_005654
- 途径
- Chromatin Binding
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