PCSK2 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all PCSK2 蛋白
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PCSK2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human NEC2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PCSK2 蛋白
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Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 1-619) protein (GST tag)
PCSK2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 501-609) protein (GST tag)PCSK2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 110-638) protein (His tag)Crystallography grade PCSK2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 109-637) protein (His tag)Crystallography grade PCSK2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- 别名
- Nec2 (PCSK2 产品)
- 别名
- NEC 2 Protein, NEC-2 Protein, NEC2 Protein, PC2 Protein, SPC2 Protein, PCSK2 Protein, 6330411F23Rik Protein, AI839700 Protein, Nec-2 Protein, Nec2 Protein, Phpp-2 Protein, pc2 Protein, nec2 Protein, spc2 Protein, pcsk2 Protein, pcsk2-A Protein, proprotein convertase subtilisin/kexin type 2 Protein, proprotein convertase subtilisin/kexin type 2 L homeolog Protein, PCSK2 Protein, pcsk2 Protein, Pcsk2 Protein, pcsk2.L Protein
- 背景
- This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The protein undergoes an initial autocatalytic processing event and interacts with a neuroendocrine secretory protein in the ER, exits the ER and sorts to secretory granules, where it is cleaved and catalytically activated during intracellular transport. The encoded protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- 分子量
- 67.9 kDa
- NCBI登录号
- NP_002585
- 途径
- Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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