MRVI1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all MRVI1 蛋白
- MRVI1 (Murine Retrovirus Integration Site 1 Homolog (MRVI1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MRVI1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human MRVI1 / IRAG (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MRVI1 蛋白
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Murine Retrovirus Integration Site 1 Homolog (MRVI1) (AA 1-885) protein (rho-1D4 tag)
Crystallography grade MRVI1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Murine Retrovirus Integration Site 1 Homolog (MRVI1) (AA 1-899) protein (rho-1D4 tag)Crystallography grade MRVI1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- MRVI1 (Murine Retrovirus Integration Site 1 Homolog (MRVI1))
- 别名
- Mrvi1,irag (MRVI1 产品)
- 别名
- BB115629 Protein, Irag Protein, Ris1 Protein, IRAG Protein, JAW1L Protein, MRV integration site 1 Protein, murine retrovirus integration site 1 homolog Protein, Mrvi1 Protein, MRVI1 Protein
- 背景
- This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used.
- 分子量
- 97.7 kDa
- NCBI登录号
- NP_001092049
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