MMP1 Protein (Transcript Variant 1) (His tag)
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- 抗原 See all MMP1 蛋白
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MMP1 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
- 特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
- 产品特性
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- Recombinant human MMP-1 (transcript variant 1) protein expressed in HEK293.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- 纯度
- > 90 % , as determined by Coomassie stained SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg of protein as determine by the LAL method.
- Biological Activity Comment
- Human MMP-1 cleaves the peptide substrate Mca-KPLGL-Dpa-AR-NH2 with an activity above 200 pmol/min/μg.
- Top Product
- Discover our top product MMP1 蛋白
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Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 23-215) protein (His tag)
MMP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 370-469) protein (GST tag)MMP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) protein (GST tag)MMP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 97-464) protein (His tag)Crystallography grade MMP1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 100-269) protein (His tag)Crystallography grade MMP1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 100-469) protein (His tag)Crystallography grade MMP1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 270-469) protein (His tag)Crystallography grade MMP1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - 说明
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The tag is located at the N-terminal.
- 限制
- 仅限研究用
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- 浓度
- > 50 μg/mL
- 缓冲液
- 25 mM TRIS, 10 mM CaCl2, 150 mM NaCl, pH 7.5
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- 别名
- Mmp-1 (MMP1 产品)
- 别名
- CLG Protein, CLGN Protein, Mmp1a Protein, CG4859 Protein, Dm1-MMP Protein, Dmel\\CG4859 Protein, MMP-1 Protein, MMP1 Protein, Mmp 1 Protein, dMMP1 Protein, dm1-MMP Protein, dmmp1 Protein, l(2)k04809 Protein, mmp1 Protein, Mmp1 Protein, Mcol-A Protein, Mcola Protein, col4 Protein, mmp18 Protein, Clgn Protein, matrix metallopeptidase 1 Protein, Matrix metalloproteinase 1 Protein, matrix metalloproteinase 1 Protein, matrix metallopeptidase 1 (interstitial collagenase) Protein, matrix metallopeptidase 1a (interstitial collagenase) Protein, matrix metallopeptidase 1 S homeolog Protein, interstitial collagenase Protein, matrix metallopeptidase 8 L homeolog Protein, MMP1 Protein, Mmp1 Protein, RB11133 Protein, Mmp1a Protein, mmp1.S Protein, LOC100727966 Protein, mmp8.L Protein
- 背景
- This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- 分子量
- 54 kDa
- NCBI登录号
- NP_002412
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