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MARCH2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

MARCH2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2725491
发货至: 中国
  • 抗原 See all MARCH2 蛋白
    MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 4
    • 1
    资源
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This MARCH2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human MARCH2 / RNF172 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MARCH2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
    别名
    March2,rnf172 (MARCH2 产品)
    别名
    MARCH-II Protein, RNF172 Protein, rgd1306395 Protein, marh2 Protein, RGD1306395 Protein, 9530046H09Rik Protein, membrane associated ring-CH-type finger 2 Protein, membrane associated ring-CH-type finger 2 S homeolog Protein, E3 ubiquitin-protein ligase MARCH2 Protein, membrane-associated ring finger (C3HC4) 2 Protein, MARCH2 Protein, march2.S Protein, march2 Protein, Tsp_09446 Protein, marh2 Protein, March2 Protein
    背景
    MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266] Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010]
    分子量
    26.8 kDa
    NCBI登录号
    NP_057580
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