MKRN1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all MKRN1 蛋白
- MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MKRN1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Makorin-1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MKRN1 蛋白
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Makorin Ring Finger Protein 1 (MKRN1) (AA 365-440) protein (GST tag)
MKRN1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Makorin Ring Finger Protein 1 (MKRN1) (AA 1-482) protein (GST tag)MKRN1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Makorin Ring Finger Protein 1 (MKRN1) (AA 1-481) protein (Strep Tag)Crystallography grade MKRN1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Makorin Ring Finger Protein 1 (MKRN1) (AA 1-482) protein (Strep Tag)Crystallography grade MKRN1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))
- 别名
- Makorin-1 (MKRN1 产品)
- 别名
- MKRN1 Protein, MGC84269 Protein, mkrn1 Protein, Makorin-1 Protein, RNF61 Protein, RFP Protein, makorin ring finger protein 1 Protein, E3 ubiquitin-protein ligase makorin-1 Protein, makorin ring finger protein 1 S homeolog Protein, makorin, ring finger protein, 1 Protein, MKRN1 Protein, LOC100393879 Protein, mkrn1.S Protein, Mkrn1 Protein
- 背景
- This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein&aposs E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 分子量
- 53.2 kDa
- NCBI登录号
- NP_038474
- 途径
- Chromatin Binding
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