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MAN2B1 Protein (Myc-DYKDDDDK Tag)

MAN2B1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2725053
发货至: 中国
  • 抗原 See all MAN2B1 蛋白
    MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 1
    资源
    • 4
    • 4
    • 1
    HEK-293 Cells
    标记
    This MAN2B1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Lysosomal Alpha-Mannosidase protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MAN2B1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1))
    别名
    Lysosomal alpha-Mannosidase (MAN2B1 产品)
    别名
    AW107687 Protein, LAMAN Protein, Laman Protein, Manb Protein, MANB Protein, mannosidase alpha class 2B member 1 Protein, mannosidase, alpha, class 2B, member 1 Protein, mannosidase 2, alpha B1 Protein, MAN2B1 Protein, man2b1 Protein, Man2b1 Protein
    背景
    This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].
    分子量
    108.7 kDa
    NCBI登录号
    NP_000519
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