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LITAF Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

LITAF 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2724835
发货至: 中国
  • 抗原 See all LITAF 蛋白
    LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 4
    • 1
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This LITAF protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human LITAF (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product LITAF 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
    别名
    Litaf (LITAF 产品)
    别名
    PIG7 Protein, SIMPLE Protein, TP53I7 Protein, EET-1 Protein, Pig7 Protein, TNF-alpha Protein, 3222402J11Rik Protein, C85531 Protein, N4WBP3 Protein, TBX1 Protein, lipopolysaccharide induced TNF factor Protein, lipopolysaccharide-induced TNF factor Protein, LPS-induced TN factor Protein, LITAF Protein, Litaf Protein
    背景
    Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
    分子量
    16.9 kDa
    NCBI登录号
    NP_004853
    途径
    Cellular Response to Molecule of Bacterial Origin
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