LIMK2 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all LIMK2 蛋白
- LIMK2 (LIM Domain Kinase 2 (LIMK2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LIMK2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human LIMK2 (transcript variant 2b) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LIMK2 蛋白
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LIM Domain Kinase 2 (LIMK2) (AA 1-638) (Active) protein (GST tag)
LIMK2 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
LIM Domain Kinase 2 (LIMK2) (AA 1-686) protein (GST tag)LIMK2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
LIM Domain Kinase 2 (LIMK2) (AA 152-252) protein (GST tag)LIMK2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
LIM Domain Kinase 2 (LIMK2) (AA 1-638) protein (Strep Tag)Crystallography grade LIMK2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
LIM Domain Kinase 2 (LIMK2) (AA 1-638) protein (Strep Tag)Crystallography grade LIMK2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- LIMK2 (LIM Domain Kinase 2 (LIMK2))
- 别名
- Limk2 (LIMK2 产品)
- 别名
- xlimk2 Protein, zgc:91990 Protein, wu:fa97c09 Protein, wu:fk73e11 Protein, LIMK2 Protein, Limk2b Protein, Link2 Protein, LIMK Protein, 9430059K01 Protein, A930024P04Rik Protein, C85310 Protein, Limk2a Protein, LIM domain kinase 2 L homeolog Protein, LIM domain kinase 2 Protein, LIM motif-containing protein kinase 2 Protein, limk2.L Protein, limk2 Protein, LIMK2 Protein, Limk2 Protein
- 背景
- There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 69.7 kDa
- NCBI登录号
- NP_057952
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