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KPNA6 Protein (Myc-DYKDDDDK Tag)

KPNA6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2724408
发货至: 中国
  • 抗原 See all KPNA6 蛋白
    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This KPNA6 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human KPNA6 / Importin alpha-7 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KPNA6 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
    别名
    Kpna6,importin alpha-7 (KPNA6 产品)
    别名
    IPOA7 Protein, Kpna5 Protein, NPI-2 Protein, KPNA7 Protein, karyopherin subunit alpha 6 Protein, karyopherin (importin) alpha 6 Protein, karyopherin alpha 6 (importin alpha 7) Protein, karyopherin alpha 6 (importin alpha 7) S homeolog Protein, KPNA6 Protein, Kpna6 Protein, kpna6.S Protein
    背景
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.
    分子量
    59.8 kDa
    NCBI登录号
    NP_036448
    途径
    Protein targeting to Nucleus
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