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INPP5E Protein (Myc-DYKDDDDK Tag)

INPP5E 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2723486
发货至: 中国
  • 抗原 See all INPP5E 蛋白
    INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
    蛋白类型
    Recombinant
    宿主
    • 2
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This INPP5E protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human INPP5E protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product INPP5E 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
    别名
    Inpp5e (INPP5E 产品)
    别名
    1200002L24Rik Protein, 72kDa Protein, mKIAA0123 Protein, CORS1 Protein, CPD4 Protein, JBTS1 Protein, MORMS Protein, PPI5PIV Protein, PMPCA Protein, inositol polyphosphate-5-phosphatase E Protein, Inpp5e Protein, INPP5E Protein
    背景
    The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms.
    分子量
    70 kDa
    NCBI登录号
    NP_063945
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