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ING3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ING3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2723448
发货至: 中国
  • 抗原 See all ING3 蛋白
    ING3 (Inhibitor of Growth Family, Member 3 (ING3))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 4
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This ING3 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human ING3 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ING3 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    ING3 (Inhibitor of Growth Family, Member 3 (ING3))
    别名
    Ing3 (ING3 产品)
    别名
    ING3 Protein, Eaf4 Protein, ING2 Protein, MEAF4 Protein, p47ING3 Protein, 1300013A07Rik Protein, P47ING3 Protein, zgc:56327 Protein, inhibitor of growth family member 3 Protein, inhibitor of growth family, member 3 Protein, inhibitor of growth protein 3 Protein, inhibitor of growth family member 3 L homeolog Protein, ING3 Protein, Ing3 Protein, CpipJ_CPIJ009396 Protein, ing3 Protein, ing3.L Protein
    背景
    The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
    分子量
    46.6 kDa
    NCBI登录号
    NP_061944
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