IKZF1 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all IKZF1 蛋白
- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IKZF1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human IKZF1 / IKAROS protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IKZF1 蛋白
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IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-477) protein (GST tag)
IKZF1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-519) protein (His tag)IKZF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-519) protein (Strep Tag)Crystallography grade IKZF1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-517) protein (Strep Tag)Crystallography grade IKZF1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
- 别名
- Ikzf1,ikaros (IKZF1 产品)
- 别名
- Hs.54452 Protein, IK1 Protein, IKAROS Protein, LYF1 Protein, PRO0758 Protein, ZNFN1A1 Protein, hIk-1 Protein, RGD1562979 Protein, ikaros Protein, znfn1a1 Protein, ik1 Protein, lyf1 Protein, hik-1 Protein, pro0758 Protein, hs.54452 Protein, MGC108252 Protein, 5832432G11Rik Protein, Ikaros Protein, LyF-1 Protein, Zfpn1a1 Protein, Znfn1a1 Protein, hlk-1 Protein, mKIAA4227 Protein, ikzf1 Protein, IKAROS family zinc finger 1 Protein, IKAROS family zinc finger 1 (Ikaros) Protein, IKZF1 Protein, Ikzf1 Protein, ikzf1 Protein
- 背景
- This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence, resulting in members with and without DNA-binding properties. Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and are thought to function as dominant-negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL).
- 分子量
- 57.3 kDa
- NCBI登录号
- NP_006051
- 途径
- Production of Molecular Mediator of Immune Response
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