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HNRNPU Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

HNRNPU 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722939
发货至: 中国
  • 抗原 See all HNRNPU 蛋白
    HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This HNRNPU protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human hnRNP-U / HNRNPU (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HNRNPU 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
    别名
    Hnrnp-U,hnrnpu (HNRNPU 产品)
    别名
    AA408410 Protein, AI256620 Protein, AL024194 Protein, AL024437 Protein, AW557595 Protein, C86794 Protein, Hnrpu Protein, SAFA Protein, Sp120 Protein, hnRNP U Protein, SN1 Protein, HNRPU Protein, SAF-A Protein, U21.1 Protein, saf-a Protein, heterogeneous nuclear ribonucleoprotein U Protein, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) S homeolog Protein, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) Protein, Hnrnpu Protein, HNRNPU Protein, hnrnpu.S Protein
    背景
    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene.
    分子量
    88.8 kDa
    NCBI登录号
    NP_004492
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