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HLA-DQB2 Protein (Myc-DYKDDDDK Tag)

HLA-DQB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722843
发货至: 中国
  • 抗原 See all HLA-DQB2 蛋白
    HLA-DQB2 (Major Histocompatibility Complex, Class II, DQ beta 2 (HLA-DQB2))
    蛋白类型
    Recombinant
    宿主
    资源
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This HLA-DQB2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human HLA-DQB2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HLA-DQB2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    HLA-DQB2 (Major Histocompatibility Complex, Class II, DQ beta 2 (HLA-DQB2))
    别名
    Hla-Dqb2 (HLA-DQB2 产品)
    别名
    HLA-DQB1 Protein, HLA-DXB Protein, major histocompatibility complex, class II, DQ beta 2 Protein, HLA-DQB2 Protein
    背景
    HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.
    分子量
    26.5
    NCBI登录号
    NP_001185787
    途径
    TCR Signaling
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