IFIH1 Protein (Myc-DYKDDDDK Tag)
(8 references)-
- 抗原 See all IFIH1 蛋白
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IFIH1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Helicard protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IFIH1 蛋白
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Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 700-1025) protein (His-IF2DI Tag)
IFIH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-221) protein (GST tag)IFIH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 928-1023) protein (GST tag)IFIH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-1025) protein (Strep Tag)Crystallography grade IFIH1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-1025) protein (Strep Tag)Crystallography grade IFIH1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "FUBP1: a new protagonist in splicing regulation of the DMD gene." in: Nucleic acids research, Vol. 43, Issue 4, pp. 2378-89, (2015) (PubMed).
: "A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128039, (2015) (PubMed).
: "The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs." in: Biochimie, Vol. 115, pp. 17-27, (2015) (PubMed).
: "Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions." in: Nature communications, Vol. 6, pp. 6669, (2015) (PubMed).
: "Anti-MDA5 antibodies in a large Mediterranean population of adults with dermatomyositis." in: Journal of immunology research, Vol. 2014, pp. 290797, (2014) (PubMed).
: "Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study." in: Arthritis research & therapy, Vol. 16, Issue 4, pp. R138, (2014) (PubMed).
: "Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway." in: Investigative ophthalmology & visual science, Vol. 55, Issue 10, pp. 6187-93, (2014) (PubMed).
: "Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study." in: Alzheimer's & dementia : the journal of the Alzheimer's Association, (2014) (PubMed).
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: "FUBP1: a new protagonist in splicing regulation of the DMD gene." in: Nucleic acids research, Vol. 43, Issue 4, pp. 2378-89, (2015) (PubMed).
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- 抗原
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
- 别名
- Helicard (IFIH1 产品)
- 别名
- MDA5 Protein, Hlcd Protein, IDDM19 Protein, MDA-5 Protein, RLR-2 Protein, 9130009C22Rik Protein, Helicard Protein, RGD1560496 Protein, interferon induced with helicase C domain 1 Protein, IFIH1 Protein, Ifih1 Protein
- 背景
- DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
- 分子量
- 116.5 kDa
- NCBI登录号
- NP_071451
- 途径
- Activation of Innate immune Response
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