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Hairless Protein (HR) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

HR 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722415
发货至: 中国
  • 抗原 See all Hairless (HR) 蛋白
    Hairless (HR)
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 3
    • 1
    资源
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This Hairless protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Hairless / HR (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HR 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    Hairless (HR)
    别名
    Hairless,hr (HR 产品)
    别名
    ALUNC Protein, AU Protein, HSA277165 Protein, MUHH Protein, MUHH1 Protein, HR Protein, N Protein, ba Protein, bldy Protein, hr Protein, rh Protein, rh-bmh Protein, rhino Protein, HR, lysine demethylase and nuclear receptor corepressor Protein, hairless Protein, HR Protein, Hr Protein
    背景
    This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene.
    分子量
    127.3 kDa
    NCBI登录号
    NP_005135
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