GSKIP Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all GSKIP 蛋白
- GSKIP (GSK3B interacting protein (GSKIP))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This GSKIP protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human GSKIP protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GSKIP 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- GSKIP (GSK3B interacting protein (GSKIP))
- 别名
- Gskip (GSKIP 产品)
- 别名
- C14orf129 Protein, 4933433P14Rik Protein, RGD1308470 Protein, C21H14orf129 Protein, C8H14orf129 Protein, wu:fc74a11 Protein, wu:fd02b09 Protein, zgc:55683 Protein, c14orf129 Protein, gskip Protein, GSK3B interacting protein Protein, gsk3b interacting protein Protein, GSK3B interacting protein L homeolog Protein, GSKIP Protein, Gskip Protein, gskip Protein, gskip.L Protein
- 背景
- This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
- 分子量
- 15.5 kDa
- NCBI登录号
- NP_057556
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