GNAS Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all GNAS 蛋白
- GNAS (GNAS Complex Locus (GNAS))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This GNAS protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human GNAS / GSP (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GNAS 蛋白
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GNAS Complex Locus (GNAS) (AA 47-245) protein (His tag)
GNAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
GNAS Complex Locus (GNAS) (AA 1-394) protein (GST tag)GNAS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
GNAS Complex Locus (GNAS) (AA 1-1037) protein (Strep Tag)Crystallography grade GNAS 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
GNAS Complex Locus (GNAS) (AA 1-394) protein (Strep Tag)Crystallography grade GNAS 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
GNAS Complex Locus (GNAS) (AA 1-394) protein (Strep Tag)Crystallography grade GNAS 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
GNAS Complex Locus (GNAS) (AA 1-1133) protein (Strep Tag)Crystallography grade GNAS 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
GNAS Complex Locus (GNAS) (AA 1-626) protein (Strep Tag)Crystallography grade GNAS 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
GNAS Complex Locus (GNAS) (AA 1-725) protein (Strep Tag)Crystallography grade GNAS 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
GNAS Complex Locus (GNAS) (AA 47-245) protein (His tag)Crystallography grade GNAS 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
GNAS Complex Locus (GNAS) (AA 47-257) protein (His tag)Crystallography grade GNAS 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- GNAS (GNAS Complex Locus (GNAS))
- 别名
- Gnas,gsp (GNAS 产品)
- 别名
- AHO Protein, C20orf45 Protein, GNAS1 Protein, GPSA Protein, GSA Protein, GSP Protein, NESP Protein, PHP1A Protein, PHP1B Protein, PHP1C Protein, POH Protein, GNAS Protein, PORGSA1 Protein, G-alpha-S Protein, 5530400H20Rik Protein, A930027G11Rik Protein, C130027O20Rik Protein, Galphas Protein, Gnas1 Protein, Gnasxl Protein, Gsa Protein, Nesp Protein, Nespl Protein, Oed-Sml Protein, Oedsml Protein, P1 Protein, P2 Protein, P3 Protein, G-alpha-s Protein, gnas-a Protein, Gnpas Protein, Nesp55 Protein, gnal Protein, Gnas Protein, GNAS complex locus Protein, guanine nucleotide-binding protein G(s) subunit alpha Protein, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus Protein, GNAS complex locus S homeolog Protein, neuroendocrine secretory protein 55-like Protein, GNAS Protein, LOC694289 Protein, LOC469986 Protein, Gnas Protein, gnas.S Protein, gnas Protein, LOC100346323 Protein, LOC100442753 Protein, LOC100732436 Protein
- 背景
- This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5&apos exons. Some transcripts contain a differentially methylated region (DMR) at their 5&apos exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
- 分子量
- 45.5 kDa
- NCBI登录号
- NP_000507
- 途径
- Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
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