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Glutaredoxin 2 Protein (GRX2) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

GRX2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722017
发货至: 中国
  • 抗原 See all Glutaredoxin 2 (GRX2) 蛋白
    Glutaredoxin 2 (GRX2)
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 6
    • 2
    • 1
    HEK-293 Cells
    标记
    This Glutaredoxin 2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Glutaredoxin-2 / GLRX2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GRX2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    Glutaredoxin 2 (GRX2)
    别名
    Glutaredoxin-2,glrx2 (GRX2 产品)
    别名
    ECK1049 Protein, JW1051 Protein, CGI-133 Protein, GRX2 Protein, 1700010P22Rik Protein, AI645710 Protein, Grx2 Protein, glutaredoxin 2 (Grx2) Protein, glutaredoxin Grx2 Protein, thioredoxin Protein, glutaredoxin 2 Protein, glutaredoxin 2 (thioltransferase) Protein, grxB Protein, grx2 Protein, AF_RS10790 Protein, GLRX2 Protein, Glrx2 Protein
    背景
    The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.
    分子量
    18.5 kDa
    NCBI登录号
    NP_057150
    途径
    Cell RedoxHomeostasis
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