Ghrelin Protein (GHRL) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
-
- 抗原 See all Ghrelin (GHRL) 蛋白
- Ghrelin (GHRL)
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This Ghrelin protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human Ghrelin / GHRL (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GHRL 蛋白
-
Ghrelin (GHRL) (AA 24-117) protein (His tag)
GHRL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Ghrelin (GHRL) (AA 24-117) protein (His-IF2DI Tag)GHRL 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Ghrelin (GHRL) (AA 24-116) protein (His tag)GHRL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Ghrelin (GHRL) (AA 1-117) protein (GST tag)GHRL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ghrelin (GHRL) (AA 24-117) protein (GST tag)GHRL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- Ghrelin (GHRL)
- 别名
- Ghrelin,ghrl (GHRL 产品)
- 别名
- 2210006E23Rik Protein, Ghr Protein, MTLRP Protein, MTLRPAP Protein, m46 Protein, Gh1-1 Protein, GRHL Protein, MTLRP-AP Protein, GHR Protein, ghrelin Protein, ghrelin and obestatin prepropeptide Protein, ghrelin/obestatin prepropeptide Protein, Ghrl Protein, GHRL Protein, ghrl Protein
- 背景
- This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.
- 分子量
- 10.4 kDa
- NCBI登录号
- NP_057446
- 途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
-
