Geminin Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all Geminin (GMNN) 蛋白
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Geminin protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Geminin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GMNN 蛋白
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Geminin, DNA Replication Inhibitor (GMNN) (AA 1-209) protein (GST tag)
GMNN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Geminin, DNA Replication Inhibitor (GMNN) (AA 110-209) protein (GST tag)GMNN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Geminin, DNA Replication Inhibitor (GMNN) (AA 1-209) protein (Strep Tag)Crystallography grade GMNN 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Geminin, DNA Replication Inhibitor (GMNN) (AA 1-206) protein (Strep Tag)Crystallography grade GMNN 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
- 别名
- Geminin (GMNN 产品)
- 别名
- CG3183 Protein, Dm Geminin Protein, Dm geminin Protein, Dmel\\CG3183 Protein, Gem Protein, Geminin Protein, anon-WO0257455.1 Protein, gem Protein, l(2)k14019 Protein, v(2)k09107 Protein, sb:cb254 Protein, zgc:66217 Protein, GB16871 Protein, GMNN Protein, geminin Protein, dyak_GLEANR_833 Protein, DyakGE24654 Protein, GE24654 Protein, LOC100049517 Protein, AW546347 Protein, geminin, DNA replication inhibitor Protein, CG3183 gene product from transcript CG3183-RA Protein, geminin Protein, GE24654 gene product from transcript GE24654-RA Protein, GMNN Protein, geminin Protein, gmnn Protein, LOC410093 Protein, Dyak\geminin Protein, Gmnn Protein
- 背景
- This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
- 分子量
- 23.4 kDa
- NCBI登录号
- NP_056979
- 途径
- EGFR Signaling Pathway, DNA Replication
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