FUBP1 Protein (Myc-DYKDDDDK Tag)
(1 reference)-
- 抗原 See all FUBP1 蛋白
- FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FUBP1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human FUBP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FUBP1 蛋白
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Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) (AA 1-653) protein (GST tag)
FUBP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) (AA 27-136) protein (GST tag)FUBP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) (AA 2-644) protein (His tag)Crystallography grade FUBP1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) (AA 2-651) protein (His tag)Crystallography grade FUBP1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "FUBP1: a new protagonist in splicing regulation of the DMD gene." in: Nucleic acids research, Vol. 43, Issue 4, pp. 2378-89, (2015) (PubMed).
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: "FUBP1: a new protagonist in splicing regulation of the DMD gene." in: Nucleic acids research, Vol. 43, Issue 4, pp. 2378-89, (2015) (PubMed).
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- 抗原
- FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))
- 别名
- Fubp1 (FUBP1 产品)
- 别名
- FBP Protein, FUBP Protein, fbp Protein, fubp Protein, MGC53183 Protein, MGC75632 Protein, FUBP1 Protein, DKFZp468N0812 Protein, 9530027K12Rik Protein, D3Ertd330e Protein, Fubp Protein, Fubp4 Protein, MGC78835 Protein, wu:fa92h11 Protein, wu:fb24h11 Protein, wu:fc26f06 Protein, zgc:66046 Protein, far upstream element binding protein 1 Protein, far upstream element (FUSE) binding protein 1 S homeolog Protein, far upstream element (FUSE) binding protein 1 Protein, far upstream element binding protein 1 L homeolog Protein, FUBP1 Protein, fubp1.S Protein, fubp1 Protein, Fubp1 Protein, fubp1.L Protein
- 背景
- The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants.
- 分子量
- 67.4 kDa
- NCBI登录号
- NP_003893
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