FKBP4 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all FKBP4 蛋白
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FKBP4 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human FKBP4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FKBP4 蛋白
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FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) protein (GST tag)
FKBP4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) (Active) protein (His tag)FKBP4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 301-410) protein (GST tag)FKBP4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) protein (His tag)FKBP4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) protein (Strep Tag)Crystallography grade FKBP4 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-458) protein (Strep Tag)Crystallography grade FKBP4 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 2-459) protein (His tag)Crystallography grade FKBP4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 2-458) protein (His tag)Crystallography grade FKBP4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- 别名
- Fkbp4 (FKBP4 产品)
- 别名
- HBI Protein, p52 Protein, hsp56 Protein, PPIase Protein, fkbp52 Protein, fkbp59 Protein, MGC81078 Protein, wu:fb34f09 Protein, 59kDa Protein, AL022792 Protein, AW208983 Protein, FKBP-4 Protein, FKBP-52 Protein, FKBP52 Protein, FKPB52 Protein, p59 Protein, FKBP51 Protein, FKBP59 Protein, Hsp56 Protein, P59 Protein, FK506 binding protein 4 Protein, FK506 binding protein 4 S homeolog Protein, FKBP4 Protein, fkbp4.S Protein, fkbp4 Protein, Fkbp4 Protein
- 背景
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene.
- 分子量
- 51.6 kDa
- NCBI登录号
- NP_002005
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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