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FcRn Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

FcRn 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2720989
发货至: 中国
  • 抗原 See all FcRn 蛋白
    FcRn (IgG receptor FcRn (FcRn))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 15
    • 6
    • 5
    • 3
    • 3
    • 1
    资源
    • 18
    • 4
    • 3
    • 3
    • 1
    • 1
    HEK-293 Cells
    标记
    This FcRn protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human FCGRT / FCRN (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FcRn 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

  • 抗原
    FcRn (IgG receptor FcRn (FcRn))
    别名
    Fcgrt,fcrn (FcRn 产品)
    别名
    FCRN Protein, alpha-chain Protein, FcRn Protein, Fc fragment of IgG receptor and transporter Protein, Fc receptor, IgG, alpha chain transporter Protein, FCGRT Protein, Fcgrt Protein
    背景
    This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
    分子量
    39.6 kDa
    NCBI登录号
    NP_004098
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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