EWSR1 Protein (Transcript Variant EWS) (Myc-DYKDDDDK Tag)
(1 reference)-
- 抗原 See all EWSR1 蛋白
- EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant EWS
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This EWSR1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human EWSR1 (transcript variant EWS) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EWSR1 蛋白
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Ewing Sarcoma Breakpoint Region 1 (EWSR1) (AA 358-453) protein (GST tag)
EWSR1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ewing Sarcoma Breakpoint Region 1 (EWSR1) (AA 1-656) protein (Strep Tag)Crystallography grade EWSR1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Ewing Sarcoma Breakpoint Region 1 (EWSR1) (AA 1-655) protein (Strep Tag)Crystallography grade EWSR1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).
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: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).
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- 抗原
- EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
- 别名
- Ewsr1 (EWSR1 产品)
- 别名
- EWS Protein, bK984G1.4 Protein, AU018891 Protein, Ews Protein, Ewsh Protein, EWSR1 Protein, fc04c01 Protein, wu:fc04c01 Protein, DKFZp459K1116 Protein, ewsr1 Protein, ewsr1.S Protein, fb40b11 Protein, fusl Protein, wu:fb40b11 Protein, wu:fb75g09 Protein, zgc:55864 Protein, EWS RNA binding protein 1 Protein, Ewing sarcoma breakpoint region 1 Protein, EWS RNA-binding protein 1 Protein, EWS RNA-binding protein 1a Protein, EWS RNA binding protein 1 L homeolog Protein, EWS RNA-binding protein 1b Protein, EWSR1 Protein, Ewsr1 Protein, ewsr1a Protein, ewsr1 Protein, ewsr1.L Protein, ewsr1b Protein
- 背景
- This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(1122)(q24q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
- 分子量
- 68.3 kDa
- NCBI登录号
- NP_005234
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