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ELAVL1 Protein (Myc-DYKDDDDK Tag)

ELAVL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2720123
发货至: 中国
  • 抗原 See all ELAVL1 蛋白
    ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
    蛋白类型
    Recombinant
    宿主
    • 3
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    • 1
    • 1
    • 1
    资源
    • 4
    • 2
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    HEK-293 Cells
    标记
    This ELAVL1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human ELAVL1 / HUR protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ELAVL1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Gorbatenko, Olesen, Loebl, Sigurdsson, Bianchi, Pedraz-Cuesta, Christiansen, Pedersen: "Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes." in: The Biochemical journal, Vol. 473, Issue 21, pp. 4027-4044, (2016) (PubMed).

    Choudhury, de Lima Alves, de Andrés-Aguayo, Graf, Cáceres, Rappsilber, Michlewski: "Tissue-specific control of brain-enriched miR-7 biogenesis." in: Genes & development, Vol. 27, Issue 1, pp. 24-38, (2013) (PubMed).

  • 抗原
    ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
    别名
    Elavl1,hur (ELAVL1 产品)
    别名
    ELAV1 Protein, HUR Protein, Hua Protein, MelG Protein, HuR Protein, 2410055N02Rik Protein, W91709 Protein, elra Protein, fa25f08 Protein, fb59a02 Protein, fc60g02 Protein, hua Protein, wu:fa25f08 Protein, wu:fb59a02 Protein, wu:fc60g02 Protein, zHuA Protein, Elavl1 Protein, Xel-1 Protein, elav1 Protein, elrA Protein, hur Protein, melg Protein, p36 Protein, ElrA Protein, elavl1 Protein, elavl1-a Protein, elavl1-b Protein, ELAV like RNA binding protein 1 Protein, ELAV-like protein 1 Protein, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) Protein, ELAV like RNA binding protein 1a Protein, ELAV like RNA binding protein 1 L homeolog Protein, ELAV like RNA binding protein 1 S homeolog Protein, ELAVL1 Protein, Elavl1 Protein, elav1 Protein, elavl1a Protein, elavl1.L Protein, elavl1.S Protein
    背景
    The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
    分子量
    35.9 kDa
    NCBI登录号
    NP_001410
    途径
    AMPK Signaling
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