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DYRK1A Protein (DYKDDDDK Tag)

DYRK1A 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2719885
发货至: 中国
  • 抗原 See all DYRK1A 蛋白
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 3
    • 1
    资源
    • 4
    • 2
    • 1
    • 1
    • 1
    Insect cells (Sf9)
    标记
    This DYRK1A protein is labelled with DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human DYRK1A (full length, C-term DDK tag, transcript variant 1) protein expressed in Sf9 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DYRK1A 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    别名
    Dyrk1a (DYRK1A 产品)
    别名
    DYRK1A Protein, dyrk Protein, dyrk1 Protein, hp86 Protein, mnb Protein, mnbh Protein, DYRK Protein, DYRK1 Protein, HP86 Protein, MNB Protein, MNBH Protein, MRD7 Protein, 2310043O08Rik Protein, D16Ertd272e Protein, D16Ertd493e Protein, Dyrk Protein, ENSMUSG00000074897 Protein, Gm10783 Protein, Mnbh Protein, Mp86 Protein, mmb Protein, PSK47 Protein, dual specificity tyrosine phosphorylation regulated kinase 1A Protein, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Protein, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a Protein, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog Protein, DYRK1A Protein, dyrk1a Protein, Dyrk1a Protein, dyrk1a.S Protein
    背景
    This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5&apos UTR or in the 3&apos coding region. These variants encode at least five different isoforms.
    分子量
    85.6 kDa
    NCBI登录号
    NP_001387
    途径
    Mitotic G1-G1/S Phases
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