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DUSP9 Protein (Myc-DYKDDDDK Tag)

DUSP9 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2719841
发货至: 中国
  • 抗原 See all DUSP9 蛋白
    DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))
    蛋白类型
    Recombinant
    宿主
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This DUSP9 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human DUSP9 / MKP4 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DUSP9 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))
    别名
    Dusp9,mkp4 (DUSP9 产品)
    别名
    MKP-4 Protein, MKP4 Protein, Dusp4 Protein, Mpk4 Protein, Pyst3 Protein, DUSP9 Protein, dual specificity phosphatase 9 Protein, DUSP9 Protein, Dusp9 Protein
    背景
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.
    分子量
    41.7 kDa
    NCBI登录号
    NP_001386
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