DMPK Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- 抗原 See all DMPK 蛋白
- DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 4
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DMPK protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human DMPK (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DMPK 蛋白
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Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-544) (Active) protein (GST tag)
DMPK 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) protein (GST tag)DMPK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) protein (Strep Tag)Crystallography grade DMPK 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-631) protein (Strep Tag)Crystallography grade DMPK 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-590) protein (His tag)Crystallography grade DMPK 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-592) protein (His tag)Crystallography grade DMPK 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
- 别名
- Dmpk (DMPK 产品)
- 别名
- DMPK Protein, DM Protein, DM1 Protein, DM1PK Protein, DMK Protein, MDPK Protein, MT-PK Protein, Dm15 Protein, DM1 protein kinase Protein, dystrophia myotonica-protein kinase Protein, DMPK Protein, Dmpk Protein
- 背景
- The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3&apos untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
- 分子量
- 69.4 kDa
- NCBI登录号
- NP_001075031
- 途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
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