DENND1B Protein (His tag)
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- 抗原 See all DENND1B 蛋白
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This DENND1B protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human DENND1B (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DENND1B 蛋白
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DENN/MADD Domain Containing 1B (DENND1B) (AA 1-396) protein (GST tag)
DENND1B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
DENN/MADD Domain Containing 1B (DENND1B) (AA 1-766) protein (Strep Tag)Crystallography grade DENND1B 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the N-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
- 别名
- Dennd1b (DENND1B 产品)
- 别名
- C1ORF18 Protein, C1orf218 Protein, FAM31B Protein, 4632404N19Rik Protein, 4930467M19Rik Protein, 6820401H01Rik Protein, F730008N07Rik Protein, Fam31b Protein, si:ch211-195i21.1 Protein, DENN domain containing 1B Protein, DENN/MADD domain containing 1B Protein, DENND1B Protein, dennd1b Protein, Dennd1b Protein
- 背景
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2 see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010].
- 分子量
- 44.8 kDa
- NCBI登录号
- NP_659414
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