DDX5 Protein (Myc-DYKDDDDK Tag)
(2 references)-
- 抗原 See all DDX5 蛋白
- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DDX5 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human DDX5 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DDX5 蛋白
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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (AA 1-614) protein (Strep Tag)
Crystallography grade DDX5 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) (AA 1-614) protein (Strep Tag)Crystallography grade DDX5 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer." in: Cell death & disease, Vol. 7, pp. e2211, (2016) (PubMed).
: "A Novel Anti-Cancer Agent, 1-(3,5-Dimethoxyphenyl)-4-[(6-Fluoro-2-Methoxyquinoxalin-3-yl)Aminocarbonyl] Piperazine (RX-5902), Interferes With β-Catenin Function Through Y593 Phospho-p68 RNA Helicase." in: Journal of cellular biochemistry, Vol. 116, Issue 8, pp. 1595-601, (2015) (PubMed).
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: "Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer." in: Cell death & disease, Vol. 7, pp. e2211, (2016) (PubMed).
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- 抗原
- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
- 别名
- Ddx5 (DDX5 产品)
- 别名
- G17P1 Protein, HLR1 Protein, HUMP68 Protein, p68 Protein, 2600009A06Rik Protein, Hlr1 Protein, wu:fa56a07 Protein, wu:fb11e01 Protein, wu:fb16c10 Protein, wu:fb53b05 Protein, ddx5 Protein, DEAD-box helicase 5 Protein, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 Protein, DEAD (Asp-Glu-Ala-Asp) box helicase 5 Protein, DEAD-box helicase 5 L homeolog Protein, DDX5 Protein, Ddx5 Protein, ddx5 Protein, ddx5.L Protein
- 背景
- DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. Alternative splicing results in multiple transcript variants.
- 分子量
- 69 kDa
- NCBI登录号
- NP_004387
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus
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