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COQ6 Protein (His tag)

COQ6 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2718741
发货至: 中国
  • 抗原 See all COQ6 蛋白
    COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
    蛋白类型
    Recombinant
    宿主
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    资源
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    大肠杆菌(E. Coli)
    标记
    This COQ6 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human COQ6 (N-term HIS tag, transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product COQ6 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
    别名
    Coenzyme q6 Homolog, Monooxygenase (S. Cerevisiae) (Coq6) (COQ6 产品)
    别名
    CGI10 Protein, COQ10D6 Protein, 5930427M12Rik Protein, AW742344 Protein, zgc:153379 Protein, coq6 Protein, coenzyme Q6, monooxygenase Protein, coenzyme Q6 monooxygenase Protein, Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Protein, coenzyme Q6 monooxygenase L homeolog Protein, COQ6 Protein, Coq6 Protein, coq-6 Protein, coq6 Protein, coq6.L Protein
    背景
    The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    分子量
    50.7 kDa
    NCBI登录号
    NP_872282
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