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HSD11B1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

HSD11B1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715551
发货至: 中国
  • 抗原 See all HSD11B1 蛋白
    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 7
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This HSD11B1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human 11-beta HSD1 / HSD11B1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HSD11B1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
    别名
    11-beta Hsd1,hsd11b1 (HSD11B1 产品)
    别名
    11-DH Protein, 11-beta-HSD1 Protein, CORTRD2 Protein, HDL Protein, HSD11 Protein, HSD11B Protein, HSD11L Protein, SDR26C1 Protein, hsd11 Protein, hsd11b Protein, LRRGT00065 Protein, hydroxysteroid 11-beta dehydrogenase 1 Protein, hydroxysteroid (11-beta) dehydrogenase 1b Protein, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog Protein, HSD11B1 Protein, HSD11B1b Protein, hsd11b1.L Protein, Hsd11b1 Protein
    背景
    The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]
    分子量
    32.2 kDa
    NCBI登录号
    NP_005516
    途径
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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