C11orf73 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all C11orf73 蛋白
- C11orf73 (Chromosome 11 Open Reading Frame 73 (C11orf73))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This C11orf73 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human C11orf73 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product C11orf73 蛋白
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Chromosome 11 Open Reading Frame 73 (C11orf73) (AA 1-197) protein (His tag)
C11orf73 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Chromosome 11 Open Reading Frame 73 (C11orf73) (AA 1-197), (full length) protein (His-SUMO Tag)C11orf73 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- C11orf73 (Chromosome 11 Open Reading Frame 73 (C11orf73))
- 别名
- c11orf73 (C11orf73 产品)
- 别名
- C11orf73 Protein, HSPC179 Protein, Hikeshi Protein, L7RN6 Protein, OPI10 Protein, Hikeshi, heat shock protein nuclear import factor Protein, Hikeshi, heat shock protein nuclear import factor L homeolog Protein, HIKESHI Protein, hikeshi.L Protein, hikeshi Protein, Hikeshi Protein
- 背景
- This gene encodes an evolutionarily conserved nuclear transport receptor that mediates heat-shock-induced nuclear import of 70 kDa heat-shock proteins (Hsp70s) through interactions with FG-nucleoporins. The protein mediates transport of the ATP form but not the ADP form of Hsp70 proteins under conditions of heat shock stress. Structural analyses demonstrate that the protein forms an asymmetric homodimer and that the N-terminal domain consists of a jelly-roll/beta-sandwich fold structure that contains hydrophobic pockets involved in FG-nucleoporin recognition. Reduction of RNA expression levels in HeLa cells using small interfering RNAs results in inhibition of heat shock-induced nuclear accumulation of Hsp70s, indicating a role for this gene in regulation of Hsp70 nuclear import during heat shock stress.
- 分子量
- 21.4 kDa
- NCBI登录号
- NP_057485
- 途径
- Protein targeting to Nucleus
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