BMP3 蛋白
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- 抗原 See all BMP3 蛋白
- BMP3 (Bone Morphogenetic Protein 3 (BMP3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
- 特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
- 产品特性
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- Recombinant human BMP3 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- 内毒素水平
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC-5 cells.
- Top Product
- Discover our top product BMP3 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - 限制
- 仅限研究用
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- 缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- 注意事项
- Resuspend the protein in the desired concentration in proper buffer
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- BMP3 (Bone Morphogenetic Protein 3 (BMP3))
- 别名
- Bmp3 (BMP3 产品)
- 别名
- BMP-3A Protein, PBMP3 Protein, 9130206H07 Protein, 9530029I04Rik Protein, BMP3 Protein, BMP-3 Protein, wu:fk96e01 Protein, zgc:153939 Protein, xBMP-3 Protein, bone morphogenetic protein 3 Protein, bone morphogenetic protein 3 L homeolog Protein, BMP3 Protein, Bmp3 Protein, bmp3 Protein, bmp3.L Protein
- 背景
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
- 分子量
- 13 kDa
- NCBI登录号
- NP_001192
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