GDF11 蛋白
GDF11
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
Func, AbP, PI, STD
Active
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- 抗原 See all GDF11 蛋白
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- 特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
- 产品特性
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- Recombinant human BMP11 / GDF11 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- 内毒素水平
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- ED50 was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.08-0.10 ug/ml.
- Top Product
- Discover our top product GDF11 蛋白
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Growth Differentiation Factor 11 (GDF11) (AA 310-407) protein (GST tag)
GDF11 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - 限制
- 仅限研究用
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- 缓冲液
- Sterile filtered through 0.2 μM filtered, Lyophilized with no additives
- 储存液
- Without preservative
- 注意事项
- Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1~1.0 mg/mL, and keep pH at acidic condition below 5.0 Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (e.g. 0.1 % BSA) and store in working aliquots at -20 °C to -80 °C
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- 别名
- Bmp11,gdf11 (GDF11 产品)
- 别名
- BMP-11 Protein, BMP11 Protein, Bmp11 Protein, GDF11 Protein, growth differentiation factor 11 Protein, GDF11 Protein, Gdf11 Protein, gdf11 Protein
- 背景
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging.
- 分子量
- 25 kDa
- NCBI登录号
- NP_005802
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