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BCAR3 Protein (Myc-DYKDDDDK Tag)

BCAR3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715176
发货至: 中国
  • 抗原 See all BCAR3 蛋白
    BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This BCAR3 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human BCAR3 / SH2D3B protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product BCAR3 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
    别名
    Bcar3,sh2d3b (BCAR3 产品)
    别名
    NSP2 Protein, SH2D3B Protein, AI131758 Protein, AND-34 Protein, BCAR3 Protein, breast cancer anti-estrogen resistance 3 Protein, breast cancer anti-estrogen resistance 3 L homeolog Protein, BCAR3 Protein, Bcar3 Protein, bcar3 Protein, bcar3.L Protein
    背景
    Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    92.4 kDa
    NCBI登录号
    NP_003558
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