Antizyme Inhibitor 1 Protein (AZIN1) (DYKDDDDK Tag)
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- 抗原 See all Antizyme Inhibitor 1 (AZIN1) 蛋白
- Antizyme Inhibitor 1 (AZIN1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Insect cells (Sf9)
- 标记
- This Antizyme Inhibitor 1 protein is labelled with DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human AZIN1 (full length, C-term DDK tag, transcript variant 1) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product AZIN1 蛋白
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Antizyme Inhibitor 1 (AZIN1) (AA 1-448) protein (GST tag)
AZIN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Antizyme Inhibitor 1 (AZIN1) (AA 339-447) protein (GST tag)AZIN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Antizyme Inhibitor 1 (AZIN1) (AA 1-448) protein (Strep Tag)Crystallography grade AZIN1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Antizyme Inhibitor 1 (AZIN1) (AA 1-448) protein (Strep Tag)Crystallography grade AZIN1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Antizyme Inhibitor 1 (AZIN1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)AZIN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Antizyme Inhibitor 1 (AZIN1)
- 别名
- Azin1 (AZIN1 产品)
- 别名
- OAZI Protein, OAZIN Protein, ODC1L Protein, 1700085L02Rik Protein, AI414949 Protein, Oazi Protein, Oazin Protein, AZIN1 Protein, azin1 Protein, oazin Protein, wu:fj32d12 Protein, MGC81852 Protein, wu:fc93f10 Protein, zgc:110131 Protein, antizyme inhibitor 1 Protein, antizyme inhibitor 1b Protein, antizyme inhibitor 1 L homeolog Protein, antizyme inhibitor 1a Protein, AZIN1 Protein, Azin1 Protein, azin1b Protein, azin1.L Protein, azin1 Protein, azin1a Protein
- 背景
- The protein encoded by this gene belongs to the antizyme inhibitor family, which plays a role in cell growth and proliferation by maintaining polyamine homeostasis within the cell. Antizyme inhibitors are homologs of ornithine decarboxylase (ODC, the key enzyme in polyamine biosynthesis) that have lost the ability to decarboxylase ornithine however, retain the ability to bind to antizymes. Antizymes negatively regulate intracellular polyamine levels by binding to ODC and targeting it for degradation, as well as by inhibiting polyamine uptake. Antizyme inhibitors function as positive regulators of polyamine levels by sequestering antizymes and neutralizing their effect. This gene encodes antizyme inhibitor 1, the first member of this gene family that is ubiquitously expressed, and is localized in the nucleus and cytoplasm. Overexpression of antizyme inhibitor 1 gene has been associated with increased proliferation, cellular transformation and tumorigenesis. Gene knockout studies showed that homozygous mutant mice lacking functional antizyme inhibitor 1 gene died at birth with abnormal liver morphology. RNA editing of this gene, predominantly in the liver tissue, has been linked to the progression of hepatocellular carcinoma. Alternatively spliced transcript variants have been described for this gene.
- 分子量
- 49.4 kDa
- NCBI登录号
- NP_056962
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