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AUH Protein (Myc-DYKDDDDK Tag)

AUH 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715079
发货至: 中国
  • 抗原 See all AUH 蛋白
    AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))
    蛋白类型
    Recombinant
    宿主
    • 2
    • 1
    资源
    • 2
    • 1
    HEK-293 Cells
    标记
    This AUH protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human AUH protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product AUH 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))
    别名
    Auh (AUH 产品)
    别名
    C77140 Protein, W91705 Protein, wu:fb81b10 Protein, zgc:101057 Protein, AU RNA binding methylglutaconyl-CoA hydratase Protein, AU RNA binding protein/enoyl-coenzyme A hydratase Protein, AU RNA binding protein/enoyl-CoA hydratase Protein, AU RNA binding protein/enoyl-CoA hydratase S homeolog Protein, AUH Protein, Auh Protein, auh Protein, auh.S Protein
    背景
    This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants.
    分子量
    29.1 kDa
    NCBI登录号
    NP_001689
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