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PRKAB2 Protein (His tag)

PRKAB2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2714673
发货至: 中国
  • 抗原 See all PRKAB2 蛋白
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This PRKAB2 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human AMPK beta-2 chain / PRKAB2 (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PRKAB2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    别名
    Ampk beta-2 Chain,prkab2 (PRKAB2 产品)
    别名
    prkab2 Protein, MGC64365 Protein, PRKAB2 Protein, DKFZp469M1118 Protein, 5730553K21Rik Protein, AW049591 Protein, BB124140 Protein, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog Protein, protein kinase AMP-activated non-catalytic subunit beta 2 Protein, protein kinase, AMP-activated, beta 2 non-catalytic subunit Protein, prkab2.L Protein, PRKAB2 Protein, prkab2 Protein, Prkab2 Protein
    背景
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
    分子量
    30.1 kDa
    NCBI登录号
    NP_005390
    途径
    AMPK Signaling, Warburg Effect
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