HOGA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all HOGA1 蛋白
- HOGA1 (4-Hydroxy-2-Oxoglutarate Aldolase 1 (HOGA1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This HOGA1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Chromosome 10 open reading frame 65 (C10orf65), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HOGA1 蛋白
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4-Hydroxy-2-Oxoglutarate Aldolase 1 (HOGA1) (AA 26-327) protein (His tag)
Crystallography grade HOGA1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, Crys, SDS, WB
4-Hydroxy-2-Oxoglutarate Aldolase 1 (HOGA1) (AA 24-321) protein (His tag)Crystallography grade HOGA1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, Crys, SDS, WB
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- HOGA1 (4-Hydroxy-2-Oxoglutarate Aldolase 1 (HOGA1))
- 别名
- Chromosome 10 Open Reading Frame 65 (c10orf65) (HOGA1 产品)
- 别名
- C10orf65 Protein, DHDPS2 Protein, DHDPSL Protein, HP3 Protein, NPL2 Protein, 0610010D20Rik Protein, Dhdpsl Protein, Npl2 Protein, 4-hydroxy-2-oxoglutarate aldolase 1 Protein, HOGA1 Protein, Hoga1 Protein
- 背景
- The authors of PMID:20797690 cloned this gene while searching for genes in a region of chromosome 10 linked to primary hyperoxalurea type III. They noted that even though the encoded protein has been described as a mitochondrial dihydrodipicolinate synthase-like enzyme, it shares little homology with E. coli dihydrodipicolinate synthase (Dhdps), particularly in the putative substrate-binding region. Moreover, neither lysine biosynthesis nor sialic acid metabolism, for which Dhdps is responsible, occurs in vertebrate mitochondria. They propose that this gene encodes mitochondrial 4-hydroxyl-2-oxoglutarate aldolase (EC 4.1.3.16), which catalyzes the final step in the metabolic pathway of hydroxyproline, releasing glyoxylate and pyruvate. This gene is predominantly expressed in the liver and kidney, and mutations in this gene are found in patients with primary hyperoxalurea type III. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
- 分子量
- 35.1 kDa
- NCBI登录号
- NP_612422
- 途径
- Monocarboxylic Acid Catabolic Process
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