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CENPB Protein (Myc-DYKDDDDK Tag)

CENPB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713906
发货至: 中国
  • 抗原 See all CENPB 蛋白
    CENPB (Centromere Protein B (CENPB))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CENPB protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CENP-B protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CENPB 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CENPB (Centromere Protein B (CENPB))
    别名
    Cenp-B (CENPB 产品)
    别名
    CENPB Protein, CENP-B Protein, centromere protein B Protein, centromere protein B, 80kDa Protein, CENPB Protein, Cenpb Protein
    背景
    This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.
    分子量
    65 kDa
    NCBI登录号
    NP_001801
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