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CDK8 Protein (Myc-DYKDDDDK Tag)

CDK8 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713871
发货至: 中国
  • 抗原 See all CDK8 蛋白
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    蛋白类型
    Recombinant
    宿主
    • 4
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    资源
    • 3
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    HEK-293 Cells
    标记
    This CDK8 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CDK8 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CDK8 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    别名
    Cdk8 (CDK8 产品)
    别名
    K35 Protein, wu:fk95h11 Protein, cyclin dependent kinase 8 Protein, cyclin-dependent kinase 8 Protein, cyclin-dependent kinase 8 S homeolog Protein, Cyclin-dependent kinase 8 Protein, cyclin dependent kinase 19 Protein, CDK8 Protein, Cdk8 Protein, cdk8 Protein, cdk8.S Protein, cdk-8 Protein, CDK19 Protein
    背景
    This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
    分子量
    53.1 kDa
    NCBI登录号
    NP_001251
    途径
    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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