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CDK2AP1 Protein (Myc-DYKDDDDK Tag)

CDK2AP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713862
发货至: 中国
  • 抗原 See all CDK2AP1 蛋白
    CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CDK2AP1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CDK2AP1 / DOC1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CDK2AP1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
    别名
    Cdk2ap1,doc1 (CDK2AP1 产品)
    别名
    MGC64532 Protein, doc1 Protein, st19 Protein, doc-1 Protein, dorc1 Protein, p12doc-1 Protein, Apc10 Protein, Cdkap1 Protein, DORC1 Protein, Doc1 Protein, ST19 Protein, p12 Protein, DOC1 Protein, p12DOC-1 Protein, cyclin-dependent kinase 2 associated protein 1 S homeolog Protein, cyclin dependent kinase 2 associated protein 1 Protein, cyclin dependent kinase 2 associated protein 1 pseudogene Protein, cyclin-dependent kinase 2 associated protein 1 Protein, CDK2 (cyclin-dependent kinase 2)-associated protein 1 Protein, cdk2ap1.S Protein, CDK2AP1 Protein, LOC475806 Protein, cdk2ap1 Protein, Cdk2ap1 Protein
    背景
    The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    分子量
    12.2 kDa
    NCBI登录号
    NP_004633
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