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ITGAL Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ITGAL 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713386
发货至: 中国
  • 抗原 See all ITGAL 蛋白
    ITGAL (Integrin alpha-L (ITGAL))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 4
    • 4
    • 1
    资源
    • 5
    • 4
    HEK-293 Cells
    标记
    This ITGAL protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CD11a / ITGAL (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ITGAL 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • De Franceschi, Peuhu, Parsons, Rissanen, Vattulainen, Salmi, Ivaska, Pouwels: "Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143423, (2015) (PubMed).

  • 抗原
    ITGAL (Integrin alpha-L (ITGAL))
    别名
    Cd11a,itgal (ITGAL 产品)
    别名
    CD11A Protein, LFA-1 Protein, LFA1A Protein, (p180) Protein, Cd11a Protein, LFA-1A Protein, Ly-15 Protein, Ly-21 Protein, CD11a Protein, ITGAL Protein, integrin subunit alpha L Protein, integrin alpha L Protein, ITGAL Protein, Itgal Protein
    背景
    ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
    分子量
    126.1 kDa
    NCBI登录号
    NP_002200
    途径
    Activated T Cell Proliferation, Integrin Complex
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