CASP5 Protein (His tag)
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- 抗原 See all CASP5 蛋白
- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CASP5 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Caspase-5 (full length, N-term HIS tag, transcript variant a) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CASP5 蛋白
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Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 309-418) protein (GST tag)
CASP5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 137-327), (partial) protein (His tag)CASP5 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 137-327), (partial) protein (His-SUMO Tag)CASP5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the N-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
- 别名
- Caspase-5 (CASP5 产品)
- 别名
- ICE(rel)III Protein, ICEREL-III Protein, ICH-3 Protein, CASP5 Protein, caspase 5 Protein, caspase-5 Protein, CASP5 Protein, LOC100437308 Protein
- 背景
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
- 分子量
- 47.7 kDa
- NCBI登录号
- NP_004338
- 途径
- Inflammasome
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